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Such measurements include: (1) the measurement of facial skin capacitance using a suitable instrument (for example, a Corneometer CM 825; Courage Khazaka Electronic, KoIn, Germany); (2) the measurement of facial skin conductance using a gabica 100mg viagra instrument (for example, a Skicon-200; ISBS Co.Hamamatsu, Japan); (3) the measurement of skin surface topography using suitable methods and instruments (for example, the generation of skin replicas of the facial area followed by analysis with a suitable instrument, for example, an optical profilometer, a laser profilometer andor a transparency profilometer); (4) the measurement of skin surface topography using high resolution photography using viagra falls hotels suitable instruments and aventurine feldspat wirkung viagra analysis (for example, the Visia System (Proctor amp; Gamble), the Primos System (GF Messtechnik GmbH, Germany), the Leica Stereo Explorer; (5) the measurement of facial skin elasticity using a suitable instrument (for example, a Cutometer SEM 575 skin elasticity meter). (6) the measurement of skin color using high resolution photography using a suitable instruments (for example, a Minolta skin analysis camera), software analysis and standardized color palettes (for example, the Pantone [Registered Trade Mark] system). Information recorded for each patient includes age (years), gender, motivation rating (somemoderategreat) and number and type of previous treatment regimens for facial skin. Volunteers taking part in this study are adults aged 18 to 65 years. Volunteers with certain characteristics are equally distributed for the topical formulation of the present invention and placebo formulation treatment. In general, the volunteers treated with placebo formulation have little or no improvement in one or more physical or biological parameters, including facial skin capacitance, facial skin conductance, parameters associated with skin surface topography such as wrinkle frequency, wrinkle depth, roughness and smoothing, and altered "skin-lightening" parameters such as skin color, skin brightness, time taken for pigment fade, whereas the volunteers treated with a topical formulation of the present invention show positive "anti-ageing" parameters in one or more of the above-mentioned physical or biological parameters at the conclusion of the study.

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