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Product Description

The present invention further enables the use of hydrophilic molecules which are incorporated within the submicron sized water droplets contained within the microemulsion, thereby enhancing transdermal delivery of desired active agents. The topical delivery system of the present invention is in the form of a microemulsion. The subject microemulsions for transdermal delivery of peptides, polypeptides and proteins or other molecules such as water soluble tesco viagra 2013 nba, NSAIDs, genetic molecules and chemical compounds are viara to be formed with little or no shear force applied to the molecules during the preparation of the microemulsion, which aids in the preservation of the structure and bioactivity of these molecules. The microemulsion also provides shiratakis donde comprar viagra a hydrophilic and hydrophobic environment, which can aid in the solubilization of various molecules and which additionally provides the ability to mix hydrophobic molecules and hydrophilic molecules within the same formulation. Additionally, the microemulsions of the present invention provide an environment which allows for the solubilization of various water- soluble molecules at a wide range of concentrations. Hence, in one aspect, the present invention provides a microemulsion comprising a water na an oil phase; an active ingredient; one or more zwitterionic surfactants; and one or more co-surfactants. In another aspect, the present invention provides a microemulsion which is capable of transdermal delivery of active agents.

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The Conversion Price is equal to the lesser of (i) 115 of the average of the two lowest bid prices quoted on the exchange where the Company's common stock is traded during the ten days preceding the closing or, (ii) 80 of the average of the two lowest bid prices of the common stock. Related to this issuance of the Company's preferred stock, the Company recorded an imputed, preferred dividend, which represented the difference between the trading price of the Company's common stock and the conversion rate most beneficial to the preferred stock holder, at the date the preferred stock was issued. The dividend amounted to 3,168,000, which is reflected as an increase in the net loss available to common shareholders on the accompanying statement of operations. The preferred stock may be redeemed by the Company at any time after closing, at a price per share equal to the greater of (a) 1,400 plus an additional amount defined as 6 of the face amount of the stock being redeemed, multiplied by the number of days since closing, divided by 365; or (b) the market price of the common stock into which the preferred stock could be converted, as of the date of the redemption. On the fourth anniversary of the issue date, any existing preferred stock must be redeemed or converted into common stock, subject to certain provisions. Pursuant to the preferred stock securities purchase agreement, the Company was required (a) not to have any suspension of trading of its common stock on the NASDAQ, and (b) file, within 30 days of the closing of the transaction, a registration statement to cover the underlying shares and warrants and such shares issuable pursuant to the anti-dilution provisions of the agreement and certain other requirements.

Sanders v. Johnson amp; Johnson2006 WL 1541033 (D. June 2, 2006) (Intergel adhesion prevention solution ‚ personal injury, medical monitoring). Nationwide class certification denied.]